Yes, they now have an indestructible 0/1 blocker, but you might have permanently dealt with their commander with no means of regaining access to it
This was before even Mana Drain
Forest Gaelicat Gigantoad Gohn, Town of Ruin Gongaga, Reactor Town Goobbue Gardener Gran Pulse Ochu Guadosalam, Farplane Gateway Gysahl Greens Haste Magic Hecteyes Hill Gigas Ice Flan Ice Magic Insomnia, Crown City Instant Ramen Iron Giant Island Item Shopkeep Laughing Mad Light of Judgment Loporrit Scout Lunatic Pandora Magic Damper Magic Pot Magitek Infantry Malboro Monk's Fist Mountain Mysidian Elder Namazu Trader Paladin's Arms Plains Prishe's Wanderings Qiqirn Merchant Qutrub Forayer Rabanastre, Royal City Red Mage's Rapier Resentful Revelation Retrieve the Esper Rook Turret Sabotender Sage's Nouliths Sahagin Scorpion Sentinel Sephiroth's Intervention Sharlayan, Nation of Scholars
Im looking at cards like Otharri, Suns' Glory, Etali, Primal Storm, and Brutal Hordechief for additional triggers from additional combat phases
This can only be done during your turn, and only once per turn