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Magician's Right Hand X SPELL Continuous Negate the effect of your opponent's first Spell Card or effect that resolves each turn while you control a Spellcaster monster, and if you do, or if it did not have an effect, destroy that card

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Q2528 Mar

Sakura-Tribe Elder is my favorite example of this, letting you play it out and absorb a bit of damage before sacrificing itself for value

Once per turn, when your opponent activates a monster effect (Quick Effect): You can negate the activation, and if you do, destroy that monster