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When GLP-1 Muscle Loss Can Become Muscle Wasting Malnutrition Risks While moderate lean-mass reduction during weight loss is a normal adaptive process , true muscle wasting can occur if the body becomes undernourished
Retatrutide is still completing its phase 3 trial program, with FDA approval estimated for 2027 or 2028
TRT/fertility-preservation use is off-label
Most adverse effects can be managed or avoided by correct patient selection with proper monitoring under expert care
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