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Patients should be aware that: No licensed combination product exists in the UK Any combination use would be considered experimental and is not supported by current evidence Clinical decisions must be guided by a qualified healthcare professional with access to current trial data Clinical Evidence and Trial Data Available to UK Patients Retatrutide Phase 2 data showed approximately 24% mean body weight reduction at the highest dose over 48 weeks, but no published trial data exist for the specific cagrilintideretatrutide combination

Small human cosmetic studies report changes in wrinkle depth and skin density, but the strongest human evidence is topical. BPC-157: Cell and animal models support blood-vessel signaling and repair-cell effects

Despite the numerous factors mentioned above, further research is still needed to explore long-term adherence and its determinants