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Available reports describe 5-Amino-1MQ as selective for NNMT within tested experimental panels, but those panels do not equal a complete off-target safety profile across all methyltransferases, non-methyltransferase proteins, cell types, exposure durations, or intracellular conditions
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If two compounds affect the same neurotransmitter system, one of them doesn't belong in the stack
5-Amino-1MQ works by precisely blocking the catalytic pocket of the NNMT enzyme
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