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It mediates important physiological effects of the endogenous peptide, GLP-1, in regulating insulin secretion, carbohydrate metabolism and appetite, and thus is well established as a long term clinical target for treating type II diabetes and obesity (Graaf et al
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Mol Cells (2018) 41(3):23443
Kauzman A, Pavone M, Blanas N, Bradley G
The three-way comparison between semaglutide, tirzepatide, and retatrutide provides the broadest perspective on the current GLP-1 landscape
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