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In 2024, the FDA approved an extended 2.0 mg dose for patients who need better blood sugar control

By using a reducible disulfide linker, we built in a redox-sensitive release mechanism to facilitate intracellular release of the unmodified NMDA receptor antagonist, enabling the combined cellular actions of GLP-1 receptor agonism and NMDA receptor antagonism

Wagner KR, Abdel-Hamid HZ, Mah JK, Campbell C, Guglieri M, Muntoni F et al (2020) Randomized phase 2 trial and open-label extension of Domagrozumab in Duchenne muscular dystrophy

Is BPC-157 approved for human use in Canada

Synaptogenesis and neural connection rebuilding Forming new neurons matters