Start your intake Understanding GLP-1 Rebound and Why Gradual Discontinuation Matters When GLP-1 medications are stopped abruptly, appetite-regulating hormones and metabolic signaling return to baseline patternsoften triggering rapid hunger, cravings, and weight regain
Central Appetite Suppression GLP-1 receptors are present in areas of the brain that regulate hunger and satiety particularly the hypothalamus and brainstem
If burping persists beyond 12 weeks, discuss dose adjustments with your PlexusDx provider
To date, these GLP-1 drugs have been approved to treat three adult populations: individuals with type 2 diabetes, individuals with a body mass index (BMI) of 30 or greater (obesity), and individuals with a BMI between 27 and 30 (overweight) with at least one weight-related health condition, such as cardiovascular disease, high blood pressure, high cholesterol, prior stroke, prior heart attack, and chest pain (angina)
Endogenous hyperinsulinemia may cause weight gain and obesity [30], and treatment with insulin causes substantial weight gain, and may even increase cardiovascular risk [31]