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From a molecular science perspective BPC-157 is examined for its interaction with cellular protection pathways involving nitric oxide signalling angiogenic factor modulation and transcriptional regulation associated with tissue integrity maintenance
Then, to determine whether the decreased levels of reduced GSH would affect sensitivity to artemisinin treatment, PfMRP1-mutant and PfDd2 parasites were pulse treated with different concentrations of DHA (100 700 nM) for 1 h and the PfMRP1 mutant was significantly more sensitive to DHA treatment compared to PfDd2 wildtype (Supp Fig 3C)
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