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Results: After 1 year of treatment using TPE with 5% albumin, UCT-MSC-EXs, Semax and Epitalon, the patients biological age was reduced by 7.9 years (from 75.93 to 68.03), and his telomere length increased from 6.45 to 6.59 kb

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Consequently, the induction of HSPs and the increased expression of uncoupling proteins may serve as neuroprotective strategies to counteract oxidative damage during periods of sleep deprivation