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Lajin, B., and A

Subcutaneous technique is straightforward: clean the site, pinch skin, insert needle at 45-degree angle, inject slowly over 30 seconds, withdraw and dispose

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It is not best suited for severe osteoarthritis, advanced cartilage loss, major joint deformity, complete tendon rupture, fracture, or injuries requiring surgical evaluation

Long-term abuse, especially by injections, might, however, damage organs or produce pigmentation problems that need medical attention