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They share a common peptide ancestor, but they are structurally and mechanistically different enough that understanding the distinction is essential for experiment design and result interpretation
Because SIBO produces endotoxins that increase intestinal permeability (sometimes called leaky gut), repairing that barrier is a key step in reducing the chance the overgrowth comes back
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doi: 10.1016/s0969-9961(03)00070-6
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