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IGF-1 influences expression of genes that regulate protein degradation, peptide processing and presentation Defects in antigen presentation have been described in PCa cell cultures 24 , involving multiple components of the APM

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An NMR lipid analysis includes a standard lipid profile, (LDL-C, HDL-C, triglycerides, and total cholesterol) plus the following important measurements: LDL particle number Number of small LDL particles HDL particle number LDL particle size An analysis of insulin sensitivity based on lipid particle chemistry Other parameters that can offer insight into cardiovascular risk associated with blood lipids include: Lipoprotein (a) Lp-PLA2 (which measures activity of an enzyme that can contribute to vascular plaque rupture) However, as stated elsewhere in this protocol, blood lipids represent only some of the factors that can contribute to cardiovascular risk

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