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As clinicians, were seeing real benefits from GLP-1 medications for the right patients especially where insulin resistance and obesity are driving disease but your caution is important
Shoulder arthritis involving cartilage degeneration and bone changes typically does not improve significantly
Exenatide and lixisenatide are primarily cleared through the kidneys, while liraglutide, dulaglutide, semaglutide, and tirzepatide undergo proteolytic degradation throughout the body with minimal renal excretion of intact drug
Supportive boosters, but not as effective as IV drips or injections
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