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As no data are available on efficacy of this formulation, we studied vitamin B12 serum levels, the physical activity scale of the RAND-36, the number of steps on an activity meter, and the fatigue and concentration scales of the CIS20r questionnaires, before and after 3 months of treatment in ME/CFS patients
This is especially relevant if you: follow a restrictive diet, like a vegan diet are over the age of 60 are pregnant or nursing have a medical condition that can deplete B12 levels take a B12-depleting medication, like metformin or proton pump inhibitors In addition to learning about your symptoms and giving you a physical exam, a healthcare professional can rule out a B12 deficiency by ordering various blood tests( If youre diagnosed with too low B12 levels, your healthcare professional will recommend the most appropriate treatment
However, detailed results from these trials have not been published in peer-reviewed journals, limiting comprehensive assessment of clinical efficacy
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