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This should raise alarms The staggeringly high discontinuation rates of GLP-1 RA should raise alarms for clinicians, policy makers, and public health experts, said Khan, associate professor of medicine (cardiology) and preventive medicine (epidemiology) at Northwestern University Feinberg School of Medicine and a Northwestern Medicine physician

Patients in the semaglutide treatment arm of STEP 1 were more likely to be exposed to the medication at the full dose of 2.4 mg than those in SELECT

Imputation was performed using a linear regression model, with sex, baseline BMI and timing of last observation as factors, and baseline value and last observation value as covariates

By avoiding risky combinations, patients ensure semaglutide delivers its intended benefits: better blood sugar control, sustainable weight loss, and reduced cardiovascular risks