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Individual metabolic factors play a significant role
The oral semaglutide product approved for weight management is Wegovy tablets at 25 mg, approved December 22, 2025, for long-term weight reduction in adults with obesity or overweight with a weight-related condition, and for cardiovascular risk reduction in adults with obesity or overweight
11 Future Perspectives 11.1 Monotherapy Given the modest weight loss delivered by SGLT2 inhibitors, it is not likely that they will be successful as monotherapies for obesity
Both classes reduce hunger, so combined use can drive caloric intake very low
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