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FM 2.0 principle : Restore cross-system communication
Intranasal delivery is of growing interest in pharmacokinetic research because it circumvents first-pass metabolism, making it ideal for exploring receptor pathway interactions in a more direct and rapid fashion
GLP-1 drugs effectively lead to drastic caloric restriction a type of weight loss that negatively impacts muscle mass
Drge and Breitkreutz, 2000
In animal models, LR3 IGF-1 was approximately 2.5-fold more potent than native IGF-1 in promoting growth, with just 44 mcg/day of LR3 producing effects equivalent to 278 mcg/day of IGF-1 (Tomas et al., 1993)
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