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Screening and follow-up are not optional.
Neither is a clinical figure
Due to the high expression profile of GLP-1R in pancreatic -cells, GLP-1 analogs (such as exendin-4) have been modified by different methods (to prolong half-life, maintain receptor binding affinity and reduce renal drug accumulation) for theranostic purposes and serve as excellent templates for future cardiovascular drug development[178-184]
34 Another promising derivative, NCX-4016, a nitric oxide-releasing aspirin derivative, demonstrated superior efficacy in a rat model of colon cancer
The FDR was calculated using a subset of false-positive proteins expected not to be labeled by LaccID: nucleus and cytosol proteins that werenot annotated with terms related to the cell surface, Golgi or membrane (Supplementary Table 4)
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