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Obesity-related comorbidities also lead to a substantial increase in US medical costs, with annual costs being $2505 higher among adults with obesity compared with those with normal weight, which totals to an estimated $260.6 billion in aggregated costs [3]

Graves Disease Graves disease is an autoimmune condition that causes hyperthyroidism, resulting from the production of TSH receptor autoantibodies that stimulate the thyroid gland to overproduce thyroid hormones [78]

Redox balance in melanocytes ROS in melanocytes ROS, which include both free radicals and their non-radical intermediates, are produced primarily by mitochondria and peroxisomes during normal cellular metabolic processes or because of exogenous prooxidant exposure 42 (Fig

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In summary, our findings identify melatonin as a regulator of ILC2 effector function through a glutathione-dependent, receptor-independent pathway