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A schematic illustration of the binding characteristics and comparative molecular interaction patterns of GLP-1 and SR18 with GLP-1R is presented in Figure 14
In patients with T2D, when analyzed separately, semaglutide and tirzepatide were associated with a greater reduction of HbA1c and FPG compared to other agents, producing a T2D remission (discontinuing pharmacological treatment) in a relevant proportion of cases
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