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However, the effect of these differences on neuronal development and function remains unknown [41]

Do not consume a daily amount of 800 mg of EGCG [(-)-epigallocatechin-3-gallate] or more

The most commonly reported side effects during the first month are gastrointestinal, including nausea, vomiting, diarrhoea, and constipation, consistent with other GLP-1-containing therapies

For clinicians, we hope these findings may prompt a more thoughtful, individualized approach when considering these therapies in higher-risk patients who have both obesity and autoimmune disease.

Providers typically begin with lower doses to help reduce gastrointestinal side effects and improve overall tolerability