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Dysesthesia, an abnormal sensation often described as tingling, burning, or numbness in the skin, appeared in 8.8% of participants on the 9 mg dose and 20.9% on the 12 mg dose, compared to just 0.7% on placebo
Approval is potentially years away, pending successful trial completion and regulatory review
Tirzepatide for managing overweight and obesity Recommendations (TA1026)
From the TSA, the 95% CIs were adjusted using the alpha spending function approach to account for type I and II errors
doi: 10.1038/s41586-018-0849-9 6 YustaBBaggioLLKoehlerJHollandDCaoXPinnellLJet al
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