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The gut microbiota in the colon is responsible for the biotransformation of primary (cholic acid, chenodeoxycholic acid) to secondary (deoxycholic, litocholic acid) and tertiary (ursodeoxycholic acid) bile acids [76]

Research in patients with atherosclerosis has shown that glutathione and vitamin C supplementation supports nitric oxide activity and may have positive effects 10

Key Takeaways Glutathione works gradually, expect subtle changes around weeks 3-4 and visible results by weeks 8-12 Consistent daily use matters more than high doses taken sporadically

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Fiolet T, Kherabi Y, MacDonald CJ, Ghosn J, Peiffer-Smadja N