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demonstrated for the first time that TMAO can bind and activate PERK to cause atherosclerosis, which provides a new mechanism of action of TMAO-induced atherosclerosis, which will be described in detail below (10)
doi:10.4103/ijem.ijem_45_24 .
doi: 10.1016/j.burns.2016.01.014 [6] Sassolas B, Haddad C, Mockenhaupt M et al
Even so, an October 2025 Gallup poll reported that 12.4% of respondents to a nationally representative survey were taking this class of medication for weight loss
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