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Exendin-4 bound to same receptors as GLP-1, stimulated insulin secretion in rodents, and lasted longer in the body thanks to a mutation that protects it from being cut up by enzymes

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In general: 48 weeks: Improvements in overall skin glow and radiance may become noticeable

- Resistance to degradation in the gastrointestinal tract

Wegovy (semaglutide) injection 2.4 mg is an injectable prescription medicine used with a reduced calorie diet and increased physical activity: to treat adults with metabolic dysfunction-associated steatohepatitis (MASH) with moderate to advanced liver scarring (fibrosis), but not with cirrhosis of the liver This indication is approved based on improvement of MASH and liver scarring (fibrosis)