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Kailera will have to demonstrate that reduction in an ongoing midstage study of the candidate for people with obesity and overweight, with a readout expected next year

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Obesity Reviews, 17(3), 251-260

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Heartburn on GLP-1 may improve with: Smaller meals Lower-fat meals Avoiding late-night eating Staying upright after meals Reducing carbonated drinks Limiting alcohol Avoiding trigger foods such as spicy meals, fried foods, chocolate, or peppermint if they worsen symptoms Discussing persistent reflux with a clinician Do not assume all upper abdominal discomfort is simple reflux