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The approval happened after participants in several GLP-1 trials experienced significant reductions in major cardiac crises, such as heart attacks and strokes, and fewer cardiovascular deaths, says Isaacs

Quick Answer: Most semaglutide side effects, particularly gastrointestinal symptoms like nausea, typically peak within 48 weeks and gradually improve over 23 months as tolerance develops

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Table 3 presents genes that are upregulated, and Table 4 presents genes that are down regulated