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Glucagon-like peptide 1 receptor agonists for the treatment of obstruc Tive sleep apnea: a meta-analysis

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115 Cerebral insulin resistance may arise from the downregulation of insulin transport across the blood-brain barrier secondary to chronic peripheral hyperinsulinemia and systemic insulin resistance 116 as well as from the loss of neuronal membrane insulin receptors induced by soluble amyloid-beta (A) oligomers

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