Side Effects and Safety Profiles Shared Side Effects Both compounds share a similar gastrointestinal (GI) side-effect profile, typical of the GLP-1 class
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Shahabi S, Esfarjani F, Reisi J, Momenzadeh S, Jami MS, Zamani S
Another study reported that subjects using liraglutide, a GLP-1 RA, had attenuated responses in the cortex and insular regions of the brain when exposed to images of food in the fasting state compared to the control group [6]
These structural differences may affect how they interact with GLP-1 receptors in the gastrointestinal tract and central nervous system, which could contribute to differences in nausea experienced