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doi: 10.1016/S2213-8587(14)70225-6 240
are inventors on a patent application covering GLP-1 analogues described here
The most commonly reported side effects were gastrointestinal, including nausea, vomiting, diarrhoea, and constipation, which were generally mild to moderate and most frequent during the dose-escalation phase
The 0.25 mg dose will reach lower peak concentrations compared to higher maintenance doses, but the time course for elimination follows the same pattern
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