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PHARMACOKINETICS Orally: - Absorption: Oral absorption of orlistat is minimal
Gruchlik A, Chodurek E, & Dzierzewicz Z
Glutathione- and glutaredoxin-dependent reduction of methionine sulfoxide reductase A [PMID: 23022439] Laboratory literature summary: Glutathione- and glutaredoxin-dependent reduction of methionine sulfoxide reductase A
The weight loss figures cited (11.8%) are from the REDEFINE 1 trial
It can be difficult to sort out hyperammonemia-induced seizure versus seizure-induced hyperammonemia
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