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Overall, the FDA has approved Semaglutide GLP-1 injections for long-term use

While GLP-1 medicines help regulate appetite and metabolism, they work best when the bodys stress response is stable

But theres a catch: Because these medications reduce appetite so effectively, people often: Eat much less overall Miss out on protein and fiber Lose muscle mass along with fat A recent JAMA Internal Medicine patient guide emphasizes that people on GLP-1 medications commonly lose both fat and lean mass, and may experience GI symptoms that make eating harder

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