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A patient describing constant, dull aching in multiple muscle groups may have medication-related myalgia, caloric-deficit-related soreness, or early hypothyroidism rather than true cramping
Monitoring liver function during treatment is crucial, given that the study did not deploy invasive liver surveillance such as biopsies
But HRV remained consistently lower regardless of exercise level fitness does not appear to offset the parasympathetic suppression
This may be due to reduced mobility from joint disease, corticosteroid use, or metabolic changes associated with chronic inflammation
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