exogenous glutathione oxidative stress Glutathione: Role in Oxidative/Nitrosative Stress, Antioxidant Defense, and Treatments - Raj Rai - 2021 It is a potent antioxidant and works in the liver to protect the body from harmful substances Glutathione - Wikipedia

Aminotransferases ALT, an intracellular enzyme formerly known as serum glutamate pyruvate transaminase, is found abundantly in the cytosol of hepatocytes, with an activity about 3,000 times greater than serum activity

There's some desensitization that can occur

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A type 3 RTA has been defined but it is no longer used as a common designation as it is a rare and transiently presenting form of RTA that shares features of both type 1 and type 2 RTA

Glutathione is the master antioxidanta protein that occurs naturally in every cell in your body