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Yoshioka N, Kuzuya T, Ito T et al (2019) Successful treatment of hepatocellular carcinoma with regorafenib after sorafenib-induced hypersensitivity
The physician may also refer the patient to another specialist if needed
A comprehensive update on the Immunoregulatory mechanisms of Akkermansia Muciniphila : insights into active ingredients, metabolites, and nutrient-driven modulation
Depending on stimuli, microglia can adopt distinct phenotypes: the M1 pro-inflammatory state (induced by lipopolysaccharide and characterized by production of cytokines such as TNF-, IL-1, and IL-6) and the M2 anti-inflammatory state (induced by IL-4 or IL-13, promoting repair) [122, 123]
In a study conducted by Kingo et al., it was observed that the mRNA expression of MITF was significantly reduced in the lesional skin of patients with vitiligo compared to healthy controls [50]
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