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Early-phase weight loss trajectories frequently do not extrapolate linearly, and many promising Phase 2 results have failed to replicate in Phase 3
These pathways are mediated through the secondary rise of Insulin-like Growth Factor 1 (IGF-1), which acts as a primary anabolic messenger in musculoskeletal tissues
Your healthcare provider may recommend dose reduction over 4-8 weeks while intensifying dietary and exercise modifications to maintain results
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