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In clinical trials for weight management (SURMOUNT-1), participants without diabetes lost approximately 15% of body weight at 5 mg, 20% at 10 mg, and 21% at 15 mg over 72 weeks

Both drug classes exert pleiotropic effects on metabolic factors, such as obesity and hypertension

Mechanism of Action Tirzepatide (brand names Zepbound and Mounjaro) and semaglutide (Ozempic, Rybelsus, and Wegovy) are glucagon-like peptide-1 (GLP-1) receptor agonists

Experts expected case delays as the Judicial Panel on Multidistrict Litigation considered how to reassign the MDL