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Results showed that semaglutide significantly reduced the risk of major adverse cardiovascular events (MACE), including death, nonfatal heart attack, and nonfatal stroke
S2CID 11894017
Underlying health conditions like insulin resistance or prediabetes may limit effects if not addressed
P.RoweD
Similarly, in LDL receptor knock-out mice subjected to a Western diet, treatment-reduced plaque lesions and semaglutide were reported to affect the expression of several genes related to cholesterol metabolism, leukocyte recruitment, adhesion and extravasation, and also extracellular matrix protein turnover [35]
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