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These molecules are not magic bullets
A 28-day, phase 1 MAD trial results in dose-dependent mean body weight reductions of 2.5%, 3.7%, 4.1%, 7.4%, and 7.8% at target doses of 0.5 mg, 1.5 mg, 5.0 mg, 7.5 mg, and 10 mg, respectively, compared to 1.8% for the placebo group (65)
Commun Biol 7 , 843 (2024)
Reduced inflammation from weight loss itself may also lower anxiety-related biomarkers, creating a secondary benefit independent of direct brain receptor activation
Providing an exogenous (external) source of glutathione before bed may support these natural "cleanup" processes
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