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They serve as messengers and system regulators in many roles
In addition, we suggest that selenium deficiency increases susceptibility to ferroptotic processes and other programmed cell death pathways due to a decrease in GPx activity [58]
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Similarly, in a xenograft mouse model, mice injected with U87-shSIRT5 cells showed notably smaller tumor volumes and reduced tumor weights compared to those xenografted with wild-type U87 cells
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