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The compound showed an in vitro NNMT IC 50 of approximately 1.2 M and did not inhibit related methyltransferases at concentrations tested
Subscribe Wilding JPH, Batterham RL, Davies M, Van Gaal LF, Kandler K, Konakli K, Lingvay I, McGowan BM, Oral TK, Rosenstock J, Wadden TA, Wharton S, Yokote K, Kushner RF
Keller U, van der Wal C, Seliger G, et al
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The next sections describe how these agents progressed through development, starting with the exendin-4 story which yielded the first approved drug, exenatide
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