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The ongoing Cardiovascular and Renal Microvascular Outcome study with Linagliptin in patients with T2DM (CARMELINA), which is powered to evaluate kidney outcomes and renoprotective effects of this inhibitor, should begin to fill in a gap in our knowledge regarding the efficacy of DPP-4 inhibitors in T2DM patients with CKD with our without CVD [130]

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1 for multiple sclerosis 2 for diabetes mellitus 1 for no discernible reason In the interval between the two data collection dates 11 patients had died or left the practice, this included both patients with diabetes

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Liraglutide LEAD 0.84-1.5%