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GPX4 catalyzes the reduction of lipid peroxides through selenocysteine (Sec) in its active center, as follows: LOOH+2GSHGPX4LOH+GSSG+H2O LOOH+2GSHGPX4LOH+GSSG+H2O The selenol group (-SeH) of selenocysteine is directly involved in electron transfer and is 100 times more catalytically efficient than regular cysteine (170)

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Compounded Methylcobalamin injections are prepared outside the FDA approval process and are not reviewed by the FDA for safety, effectiveness, or quality