A human repeat insult patch test of 100% pure sterols in 50 subjects produced no irritation/sensitization, and guinea pig maximization testing was also negative
GSSG is reduced back to GSH by the enzyme glutathione reductase, which also requires NADPH as a cofactor
Like other skincare, nutrition levels, genetics, sun exposure, and reasons for skin pigmentation

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You can reduce the "toxic load" by: Switching to non-toxic household cleaners and personal care products