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P-rank scores show that SGLT-2 inhibitors were ranked first in reducing renal outcome (100%) (Additional file 1: Table S2)

Many people who take GLP-1s don't get hunger and thirst signals as often as they would off of the medication, Lofton said

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This means that in terms of pure metabolic correction, moderate dosing was already delivering much of the effect, while higher doses primarily amplified weight loss outcomes

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