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It is synthesised in the cytosol by glutamate-cysteine ligase (EC 6.3.2.2) and glutathione synthetase, with the first, rate-limiting step feedback-inhibited by glutathione itself and intracellular concentrations typically 1 to 8 mM (Griffith, Free Radical Biology and Medicine, 1999)
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DPP-4 is responsible for degradation of B-type natriuretic peptide (BNP, Brandt et al
Optimal nutrition yields optimal results
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