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Removal of protecting groups: After completing the amino acid coupling reaction, the protecting group in the amino acid needs to be removed

This supports that the short-term anti-diabetic effect of GLP-1 is mainly due to slowing of gastric emptying and consequently a reduced rate of carbohydrate absorption

Sfara A, Dumitrascu DL

Fu Z, Sun H, Wu Y, Li C, Wang Y, Liu Y

Cagrilintide: fatty acid acylation (like semaglutide's engineering) enabling albumin binding and 7-day half-life with once-weekly dosing, approximately 11% weight loss as monotherapy