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The FDA prescribing information includes pancreatitis as a warning for semaglutide
The Medicines and Healthcare products Regulatory Agency (MHRA) regulates these medications, and NICE provides guidance on their use within the NHS
Alcohol is not strictly contraindicated, but tolerance changes significantly on GLP-1 medications
While the risk of pancreatitis has been known since clinical trials, more evidence is emerging that medicines such as Ozempic can be associated with other gastrointestinal complications that can have serious consequences such as gastroparesis (stomach paralysis) and ileus (bowel obstruction through more generalised intestinal paralysis)
It mimics the action of GLP-1, a hormone produced in the intestines that stimulates insulin secretion and suppresses glucagon release
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