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ASF1A-dependent P300-mediated histone H3 lysine 18 lactylation promotes atherosclerosis by regulating EndMT

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Of 41,792 patients who discontinued and had post-discontinuation weight data, 1-year reinitiation was lower in patients without T2D (36.3% restarted within a year) compared to those with T2D (47.3% restarted within a year)